For as long as we can remember, coffee has been promoted as a magic drink which offers a long list of health benefits, as well as health risks. While caffeine keeps workers and students awake during critical time, coffee also contains antioxidants and other active substances that may reduce internal inflammation and protect against disease.
Besides giving you an energy boost, researchers have claimed that drinking coffee could improve your longevity. From less likely to die from coronary heart disease, stroke, diabetes and kidney disease to reducing chances of getting colon cancer and Parkinson’s disease, coffee has become a favourite morning beverage with consumption hitting nearly 176 million 60-kilogram bags annually.
However, at the same time, caffeine also reduces the absorption of manganese, zinc, iron, copper, calcium, vitamin A, B12, B6, C and D, as well as other essential minerals and nutrients. That’s why you will be asked about consumption of coffee or tea when your annual blood test shows signs of osteoporosis because caffeine can interfere with the absorption of calcium.

Likewise, research showed that drinking a cup of coffee or tea with a hamburger meal reduced iron absorption by 39% and 64%. Therefore, consuming too many caffeinated drinks can lead to some dangerous side effects. While various studies have discovered that there’s a link between vitamin and mineral absorption levels, now there’s a new research about the best time to drink coffee for longevity benefits.
According to a comprehensive study published in the European Heart Journal published on January 8, 2025, people who drink coffee in the morning are less likely to die from cardiovascular disease and have a lower overall risk of death compared to those who drink coffee throughout the day. The research was carried out on the coffee consumption habits and health outcomes of over 40,000 adults.
The research, led by Dr. Lu Qi, a professor and HCA Regents Distinguished Chair at Tulane University’s School of Public Health and Tropical Medicine, included 40,725 adults taking part in the US National Health and Nutrition Examination Survey (NHANES) between 1999 and 2018. In the study, participants were asked about all the food and drink they consumed on at least one day, including whether they drank coffee, how much, and when.

Both caffeinated and decaffeinated coffee was included during the study, and timing was categorized in three periods: morning (from 4 a.m. to 11:59 a.m.), afternoon (from 12 p.m. to 4:59 p.m.) and evening (from 5 p.m. to 3:59 a.m.). The researchers identified two patterns of timing of consumption – morning and all day. By the end of the median follow-up period of nearly 10 years, there were 4,295 deaths from all causes, 1,268 from cardiovascular disease and 934 from cancer.
Dr. Lu Qi explained – “Research so far suggests that drinking coffee doesn’t raise the risk of cardiovascular disease, and it seems to lower the risk of some chronic diseases, such as type 2 diabetes. Given the effects that caffeine has on our bodies, we wanted to see if the time of day when you drink coffee has any impact on heart health.”
Around 36% of people in the study were morning coffee drinkers (drank coffee before midday), 16% of people drank coffee throughout the day (morning, afternoon, and evening) and 48% were not coffee drinkers. Compared with people who did not drink coffee, morning coffee drinkers were 16% less likely to die of any cause and 31% less likely to die of cardiovascular disease.

Interestingly, there was no reduction in risk for all-day coffee drinkers compared to non-coffee drinkers. The study also found that morning coffee drinkers benefitted from the lower risks whether they were moderate drinkers (two to three cups) or heavy drinkers (more than three cups). Light morning drinkers (one cup or less) benefitted from a smaller decrease in risk.
Dr. Qi said – “This is the first study testing coffee drinking timing patterns and health outcomes. Our findings indicate that it’s not just whether you drink coffee or how much you drink, but the time of day when you drink coffee that’s important. We don’t typically give advice about timing in our dietary guidance, but perhaps we should be thinking about this in the future.”
“This study doesn’t tell us why drinking coffee in the morning reduces the risk of death from cardiovascular disease. A possible explanation is that consuming coffee in the afternoon or evening may disrupt circadian rhythms and levels of hormones such as melatonin. This, in turn, leads to changes in cardiovascular risk factors such as inflammation and blood pressure,” – said Dr. Lu Qi.

Professor Thomas F. Lüscher from Royal Brompton and Harefield Hospitals, London, UK offers his opinion – “Why would time of the day matter? In the morning hours there is commonly a marked increase in sympathetic activity as we wake up and get out of bed, an effect that fades away during the day and reaches its lowest level during sleep.”
“Thus, it is possible that coffee drinking in the afternoon or evening disrupts the circadian rhythm of sympathetic activity. Indeed, many all-day drinkers suffer from sleep disturbances. In this context, it is of interest that coffee seems to suppress melatonin, an important sleep-inducing mediator in the brain. Overall, we must accept the now substantial evidence that coffee drinking, particularly in the morning hours, is likely to be healthy. Thus, drink your coffee, but do so in the morning!” – said Lüscher.
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January 13th, 2025 by financetwitter
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